Table 1 Sample characteristics of patients included by treatment group
SHAM (n = 19) | ACTIVE (n = 17) | Total (N = 36) | p1 | |
|---|---|---|---|---|
Age, mean (SD), y | 25.9 (6.8) | 24.8 (5.9) | 25.4 (6.3) | 0.58 |
Gender: female, n (%) | 17 (89.5) | 15 (88.2) | 32 (88.9) | 0.60 |
Handedness: right, n (%) | 15 (78.9) | 14 (82.4) | 29 (80.6) | 0.96 |
Smoking ‘yes’, n (%) | 11 (57.9) | 9 (52.9) | 20 (55.6) | 0.80 |
Years of education (school, university, or occupational training), mean (SD) | 14.3 (2.2) | 13.6 (2.4) | 14 (2.3) | 0.38 |
Employed, n (%) | 11 (57.9) | 7 (41.2) | 18 (50.0) | 0.51 |
Years after first BPD diagnosis, mean (SD) | 1.5 (3.1) | 2.0 (4.9) | 1.7 (4.0) | 0.72 |
BSL sum score, mean (SD) | 44.6 (16.6) | 39.9 (15.8) | 42.4 (16.2) | 0.39 |
BDI, mean (SD) | 32.8 (10.2) | 32.5 (12.4) | 32.6 (11.2) | 0.93 |
MADRS total score, mean (SD) | 20.7 (5.1) | 21.3 (5.6) | 21 (5.3) | 0.76 |
MADRS item 10 (suicidal thoughts), mean (SD) | 1.3 (0.8) | 1.3 (0.8) | 1.3 (0.8) | 0.94 |
SCS, mean (SD) | 2.0 (0.7) | 2.1 (0.5) | 2.0 (0.6) | 0.85 |
BIS-15, mean (SD) | 39.1 (5.8) | 40.0 (8.0) | 39.5 (6.9) | 0.69 |
- Non-planning impulsivity | 12.9 (3.0) | 13.0 (2.8) | 13.0 (2.9) | 0.93 |
- Motor impulsivity | 13.5 (2.4) | 13.7 (3.5) | 13.6 (2.9) | 0.81 |
- Attentional impulsivity | 12.1 (2.8) | 12.5 (2.6) | 12.3 (2.7) | 0.70 |
GAF, mean (SD) | 54.5 (14.1) | 52.3 (13.3) | 53.5 (13.6) | 0.63 |
MCQ, mean (SD) | 0.03469 (0.0767) | 0.01072 (0.01588) | 0.02338 (0.05734) | 0.20 |
MCQlog2, mean (SD) | -2.34222 (0.97617) | -2.63338 (0.8883) | -2.47971 (0.93409) | 0.36 |
MCQ Consistency, mean (SD) | 0.90253 (0.09737) | 0.9281 (0.06207) | 0.91461 (0.08249) | 0.36 |
MCQ proportion ‘Late Delayed Reward’, mean (SD) | 0.51267 (0.22504) | 0.62309 (0.23286) | 0.56481 (0.23229) | 0.16 |
Psychotropic drugs, n (%) | ||||
None | 7 (36.8) | 4 (23.5) | 11 (30.6) | 0.48 |
Any antidepressant | 12 (63.2) | 10 (58.8) | 22 (61.1) | 0.79 |
- SSRI | 7 (36.8) | 1 (5.9) | 8 (22.2) | 0.044 |
- SNRI | 2 (10.5) | 6 (35.3) | 8 (22.2) | 0.114 |
Any antipsychotic (AP) | 2 (10.5) | 5 (29.4) | 7 (19.4) | 0.22 |
- Second generation AP | 0 (0) | 4 (23.5) | 4 (11.1) | 0.040 |
Sum ACTIVE / SHAM sessions, mean (SD) | 18.2 (1.5) | 18.5 (1.3) | 18.3 (1.4) | 0.50 |
Resting motor threshold, mean (SD) | 51.1 (12.9) | 49.8 (11.0) | 50.5 (11.9) | 0.75 |
iTBS stimulus intensity, mean (SD) | 40.8 (10.4) | 39.6 (8.8) | 40.2 (9.6) | 0.72 |
Self-assessed treatment, n (%) | 0.35 | |||
- unknown / unsure | 4 (21.1) | 2 (11.8) | 6 (16.7) | |
- SHAM | 8 (42.1) | 4 (23.5) | 12 (33.3) | |
- ACTIVE | 7 (36.8) | 11 (64.7) | 18 (50.0) |